Common ailments in domestic guinea pigs include respiratory tract infections, diarrhea, scurvy (vitamin C deficiency, typically characterized by sluggishness), abscesses due to infection (often in the neck, due to hay embedded in the throat, or from external scratches), and infections...
How Veterinarians Diagnose Vitamin C Deficiency in Guinea Pigs. Physical exam: most common and can be considered confirmatory when paired with a thorough history. Radiographs (X-rays). Serum ascorbic acid concentrations (a blood test to check vitamin C levels).
vitamin C, and doses of vitamin C that provide adequate to saturating plasma vitamin C status in these patients appear to have beneficial effects on patient outcomes.Effects of chronic ascorbic acid deficiency on guinea pig lysosomal hydrolase activities. J. Nutr. 110, 20852094.

The results of this investigation demonstrate that guinea-pigs with marginal vitamin C deficiency provide a suitable model for studying the effect of vitamin C on somatotropin action.
Maternal vitamin C deficiency during pregnancy can have serious consequences for the fetal brain. And once brain damage has occurred, it cannot be reversed by vitamin C supplements after birth.

Such details provide a deeper understanding and appreciation for Effect Of Vitamin C Deficiency On Guinea Pig Behavior.
Male guinea pigs were fed vitamin C-deficient diets for 16 days to deplete body L-ascorbic acid (AsA) pools and then fed the deficient diet supplemented with DHA and/or AsA intraperitoneally for 14 days.