Using Glp-1 Analogs To Manage Twin-To-Twin Transfusion Syndrome

Indeed, the further association of the pathogenic mechanisms involved in twin-to-twin transfusion syndrome placenta with several molecules and pathways, such as vascular endothelial growth factor and the reninangiotensin system, makes it difficult to understand the underlying pathological conditions. bstract Since a 2004 randomized trial established fetoscopy as the gold standard for the treatment for twin-to-twin transfusion syndrome (TTTS), advancements in surgical technique and expert training have considerably improved survival rates to 89% for at least one fetus and 65% for both fetuses. However, many challenges remain. Twin-to-twin transfusion syndrome (TTTS) is a rare pregnancy condition affecting identical twins or other multiples. TTTS occurs in pregnancies where twins share one placenta and a network of blood vessels that supply oxygen and nutrients essential for development in the womb. Figure 1 Fetoscopic views during laser intervention for twin-to-twin transfusion syndrome. (A) Visualization of the amniotic membrane, stuck to the donor fetus, giving it this characteristic smooth and translucent appearance. Twin-to-twin transfusion syndrome (TTTS) is a severe complication of monochorionic twin pregnancies caused by unbalanced placental vascular anastomoses. Fetoscopic laser photocoagulation (FLP) is the standard treatment, although neonatal outcomes remain variable. This review aimed to summarize immediate, short-term, and long-term neonatal outcomes following FLP for TTTS. A narrative review of ... Twin-twin transfusion syndrome (TTTS) affects approxi-mately 15% of monochorionic pregnancies [1] and results in poor outcomes without treatment [2, 3]. TTTS is a multi-system disease resulting from volume imbalance and hormonal factors traversing placental vascular anasto-moses, contributing to profound hemodynamic shifts for both donor and ... Race Against Time: Innovative Treatment Saves Girls with Twin-to-Twin Transfusion Syndrome Chelsea Donley was at a sixteen-week prenatal appointment when she learned from her physician at University of Florida (UF) Health Jacksonville that the twins she was carrying suffered from twin-to-twin transfusion syndrome (TTTS).

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